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Adlyfe is developing novel tests for the detection of human neurodegenerative diseases.

Alzheimer's Disease: We are in early development of our assay for a-beta amyloid protein. We have designed and tested new ligands that detect amyloid formation from the target protein, a-beta, and are currently evaluating our ability to detect amyloids from Alzheimer's patients in both IVD and imaging formats.

Sporadic and variant Creutzfeldt - Jakob disease (sCJD, vCJD): We are developing a novel test for screening for the presence of misfolded prion proteins (PrPsc). We have demonstrated detection in human clinical samples of sCJD and will be testing archival tissues and of patients definitively diagnosed with vCJD disease.

Animal TSE Diseases: Scrapie, Bovine Spongiform Encephalopathy, CWD: We have demonstrated the ability to detect prion misfolded protein (PrPsc) in of animals with known disease (confirmed by matching brain tissue and Western Blot analysis with matching plasma samples.